The ECSA Citizen Science Conference 2016 aims at policy makers, science funders, scientists, practitioners in the field of citizen science, Non-Governmental Organisations and interested citizens. This trans-disciplinary conference will highlight, demonstrate and debate the innovation potential of citizen science for science, society and policy and its role within open science and innovation. The three-day conference will provide the arena to showcase how both new and traditional ways of citizens working with scientist can enable transformative potential to enhance science-policy and social impact, scientific advancement, scientific literacy and empowerment. Of particular importance will the role of citizen science within wider agendas such as ensuring open science and innovation, and progressing towards responsible research and innovations.